The Link Between Ovarian And Breast Ca.ncer

Breast and ovarian cancers are two of the most common cancers affecting women. Although these diseases originate in different parts of the body, researchers have long recognized a strong biological link between them—especially through genetics.

One of the clearest connections is found in mutations in the BRCA1 and BRCA2 genes. These genetic alterations significantly increase the risk of both breast and ovarian cancer.

According to the American Cancer Society, women diagnosed with breast cancer have a higher likelihood of developing ovarian cancer. In fact, breast cancer patients are estimated to be twice as likely to develop ovarian cancer during their lifetime.

Cleveland Clinic

BRCA Gene Risks

• Women with a BRCA1 mutation have up to a 72% lifetime risk of breast cancer and up to a 44% risk of ovarian cancer.
• Those with a BRCA2 mutation face up to a 69% risk of breast cancer and a 17% risk of ovarian cancer.

These mutations can be inherited from either parent, meaning that a family history of breast or ovarian cancer can raise your personal risk—even if no relative has had both types.

Genetic Testing and Prevention

Women from families with a strong history of either cancer may consider genetic testing for BRCA mutations. Understanding your genetic profile can help you and your healthcare provider develop a personalized plan for prevention, screening, and early detection.

Additional Risk Factors

Other shared risk factors for both cancers include:

• Increasing age
• Obesity
• Never becoming pregnant or carrying a pregnancy to term
• Long-term use of hormone replacement therapy (HRT) after menopause

Prevention and Risk Reduction

Some high-risk women opt for preventive surgeries, such as:

• Mastectomy – surgical removal of the breasts
• Oophorectomy – removal of the ovaries and fallopian tubes

In certain cases, medications like tamoxifen may be prescribed to lower the risk of breast cancer.

Taking proactive steps—such as regular screenings, lifestyle changes, and discussing your family history with your doctor—can play a crucial role in reducing cancer risk.

Share this important information with your loved ones to raise awareness and encourage early action.